Haizi Zheng

Haizi Zheng

Company: Regeneron Pharmaceuticals Inc

Job title: Principal Scientist - Bioinformatics


InferLOH: Assessing CRISPR-Induced Copy-Neutral Loss-of-Heterozygosity Prevalence Through Single-Cell RNA Sequencing 9:30 am

CRISPR-based genome editing may lead to copy-neutral loss-of-heterozygosity (LOH) occurring from the site of CRISPR editing to the telomere of the same chromosome arm. LOH could have serious health-related implications Most existing LOH assessment methods rely on cell cloning, which may not be applicable for primary cells. In addition, the methods are usually labor- and…Read more

day: Conference Day Two

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