Haizi Zheng

Company: Regeneron Pharmaceuticals

Job title: Principal Scientist - Bioinformatics

Seminars:

InferLOH: Assessing CRISPR-Induced Copy-Neutral Loss-of-Heterozygosity Prevalence Through Single-Cell RNA Sequencing 9:00 am

CRISPR-based genome editing may lead to copy-neutral loss-of-heterozygosity (LOH) occurring from the site of CRISPR editing to the telomere of the same chromosome arm. LOH could have serious health-related implications Most existing LOH assessment methods rely on cell cloning, which may not be applicable for primary cells. In addition, the methods are usually labor- and…Read more

day: Conference Day Two