Human Genetic Diversity Altering Off-Target Outcomes of Therapeutic Gene Editing

Time: 11:00 am
day: Conference Day Two


  • Exploring the application of CRISPR gene editing to modify DNA sequences in somatic cells to treat disease
  • Evaluation of analytical methods used for predicting off-target impacts including reference genomes and individual genetic variants, such as singlenucleotide polymorphisms (SNPs) and indels
  • Building a comprehensive approach by incorporating genetic variants into offtarget assessments to enhance the evaluation of therapeutic genome editing