Carl Co

Company: Arbor Biotechnologies

Job title: Senior Director - Analytical Sciences

Seminars:

Characterizing the Composition & Integrity of LNP-Based Gene Editing Therapies 2:45 pm

Highlighting key physiochemical analytical challenges in LNP-mediated gene editing formulations Analytical techniques for characterizing the DS and DP Developing a toolbox to assess the stability of LNP-based gene editing cargoRead more

day: Conference Day Two

Examining Analytical Requirements for Lipid Nanoparticle Formulations for CRISPR Delivery 2:00 pm - 4:00 pm

Highlighting the main formulations of lipid nanoparticles (LNPs) used for CRISPR delivery in mRNA, plasmid, and RNP forms How does LNP decoration impact biodistribution and analytical strategy? Effectively characterizing cargo, including guide-mRNA ratios and degradation levels How to account for inherent variability in LNP variability when designing assays to measure efficacy Developing CQAs and phase…Read more

day: Pre-Conference Workshop Day